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Chromosomal fragile sites (FSs) - HIV integration positions | 57152

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Chromosomal fragile sites (FSs) - HIV integration positions

Abanoub Raafat Samy

Chromosomal fragile sites (FSs) are loci where gaps and breaks may occur and are preferential integration targets for some viruses, for example, Hepatitis B, Epstein-Barr virus, HPV16, HPV18, and MLV vectors. However, the integration of the human immunodeficiency virus (HIV) in Giemsa bands and in FSs is not yet completely clear.