உடல்நலம் மற்றும் மருத்துவ ஆராய்ச்சி இதழ்

Atypical Hemolytic Uremic Syndrome in a One-YearOld Male Patient, Successfully Treated with Eculizumab

Henri Fero

Atypicalhemolyticuremicsyndromeis a rare form of thromboticmicroangiopathiesresulting from variousgeneticmutations of the complementfactors.

Thromboticmicroangiopathies include Thromboticthrombocytopenicpurpura, primary HUS furtherdividedintotypical HUS or Shiga-toxinrelated HUS, atypical HUS and secondaryforms of HUS. The most common clinicalfeatures of the HemolyticUremicSyndrome are: kidneyfailure, thrombocytopeniaresulting in hemorrhagicphenomena and alsointravascularhemolytic anemia. Mostcommonly HUS is a diagnosis made from excludingallotherplausiblecauses.