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A Scholarly Review of Estradiol and Alzheimer's Disease | 103786

மருத்துவ மற்றும் பரிசோதனை உளவியல்

சுருக்கம்

A Scholarly Review of Estradiol and Alzheimer's Disease

Kelli Kemenah Mauric

Alzheimer’s Disease is the most common neurodegenerative disease in the worldwide classified as both a genetic and environmental disease similar to hypertension, cardiovascular disease, major depression and schizophrenia. In 1906, a German psychiatrist named, Dr Alois Alzheimer, followed a case of a 51-year-old woman with aphasia, memory loss and behavior disturbance over several years. Upon her death, Dr. Alzheimer recorded notes of her postmortem brain autopsy that included “intracellular neurofibrillary tangles and neurotic amyloid plagues. Dr Alzheimer’s original clinical notes and postmortem brain pathology records were recovered in 1997. All notes and records concluded the 51- year-old woman had the modern diagnostic criteria of a disease more specific than current 1999 categories of neurosyphilis, vascular dementia, and senile dementia. Emil Kraeplin suggested to name the disease after Dr. Alzheimer. Alzheimer’s disease was classified as a neurological disease with cognitive loss in multiple brain areas associated with verbal deficits, memory loss, behavioral and psychiatrist deficits occurring as early as 50 years old. At the time, US estimated 5%-7% of 65 or older elderly had some cognitive deficit and by age 85 47% had significant cognitive deficits requiring long term care facilities equivalent to 4 million cases 85 billion per year in long term care facility costs to Medicare and Medicaid.

மறுப்பு: இந்த சுருக்கமானது செயற்கை நுண்ணறிவு கருவிகளைப் பயன்படுத்தி மொழிபெயர்க்கப்பட்டது மற்றும் இன்னும் மதிப்பாய்வு செய்யப்படவில்லை அல்லது சரிபார்க்கப்படவில்லை.