Bullock T*, Steele RB, Weiffenbach A, Fernandez A, and Charles K
Eosinophilic Dermatosis of Hematologic Malignancy (EDHM) is a rare cutaneous reaction associated with hematologic malignancies, including Chronic Lymphocytic Leukemia (CLL). The lesions clinically and histologically resemble insect bites; however, in most cases the patients strongly deny any history of such bites. Treatment modalities vary, though systemic steroids are most commonly used. Because EDHM can be associated with a more aggressive malignancy course, careful monitoring of patients with this eruption is essential. We present a severely pruritic, rapid onset cutaneous eruption initially thought to be a drug or bug bite reaction but ultimately presented as EDHM.